| What
is Cholinergic Urticaria?
Cholinergic urticaria is a relatively common
disorder of the immune system characterized by an immediate
skin reaction to heat, emotional stress, and/or exercise.Cholinergic
urticaria occurs in both men and women, but it seems to be
more common in men than in women. Cholinergic urticaria is
one of the physical urticarias brought on by a physical stimulus.
Although the physical stimulus might be considered to be heat,
the actual precipitating cause is sweating.
Cholinergic urticaria is the rash caused by
sweating results in a distinct red rash consisting of hives
that are 2-5 mm in diameter. It occurs after exercise even
though sweating due to stress can provoke a attack.
What causes Cholinergic Urticaria ?
Here are the list of common causes ofCholinergic
Urticaria
* Allergic or non-allergic; massive histamine
release from mast cells in superficial dermis
* Drug reaction (any drug) either from allergy or idiosyncrasy
* Food or food additive allergy
* Inhalant, contact, or ingestant allergy
* Transfusion reaction
* Insect bite, sting
* Physical trauma (heat, cold, sunlight, etc.)
* Emotional stress (reported; little supporting evidence)
Infection - viral upper respiratory infections
(especially in children) and infectious mononucleosis, viral
hepatitis; bacterial (strep throat, sinusitis, dental abscess,
otitis); vaginitis; fungal (tineas); helminthic; protozoan.
Helicobacter pylori has been increasingly associated with,
and its eradication may stop, chronic urticaria.
Cholinergic Urticaria Treatment:
There is no medical cure for Cholinergic Urticaria.
The condition can be controlled with strong medications. Cholinergic
Urticaria sometimes gets better on its own and can even disappear
completely after a few years.
* UV light has been beneficial in some
patients, but one must be circumspect about contraindications
to UV light.
* Danazol can be beneficial ostensibly
because it elevates antichymotrypsin levels.
* For patients with both cold urticaria
and cholinergic urticaria, ketotifen (where available) may
be helpful. About 62% of patients experience a reduction in
wheals, and 68% of patients report reduced itching. Cardiorespiratory
symptoms also reportedly respond to ketotifen.
What
is Urticaria ?|Classification
of Urticaria|Chronic
Idiopathic Urticaria|Cholinergic
Urticaria|
Cold
Urticaria| Urticaria
causes|Traditional
Chinese Medicine and Urticaria|Pressure
Urticaria|
Solar
urticaria
|